This medication is
a combination of omeprazole and sodium bicarbonate. It is used
to treat certain stomach and esophagus problems (such
as acid reflux, ulcers). It is also used to prevent stomach bleeding
in very ill patients.
works by decreasing the amount of acid your stomach makes. It belongs to a
class of drugs known as proton pump inhibitors (PPIs). Sodium bicarbonate is
an antacid that reduces stomach acid and helps omeprazole to work better. This
medication relieves symptoms such as heartburn, difficulty swallowing, and
persistent cough. It helps heal acid damage to the stomach and esophagus,
helps prevent ulcers, and may help prevent cancer of the esophagus.
you are self-treating with this medication, over-the-counter omeprazole/sodium
bicarbonate products are used to treat frequent heartburn (occurring
2 or more days a week). Since it may take 1 to 4 days to have full effect,
these products do not relieve heartburn right away.
over-the-counter products, carefully read the package instructions to make sure
the product is right for you. Check the ingredients on the label even if you
have used the product before. The manufacturer may have changed the
ingredients. Also, products with similar brand names may contain different
ingredients meant for different purposes. Taking the wrong product could harm
Headache or abdominal
pain may occur. If any of these effects persist or worsen, tell your
doctor or pharmacist promptly.
your doctor has directed you to use this product, remember that he or she has
judged that the benefit to you is greater than the risk of side effects. Many
people using this medication do not have serious side effects.
your doctor right away if any of these unlikely but serious side effects occur:
swelling of the hands/feet, symptoms of a low magnesium blood level
(such as unusually fast/slow/irregular heartbeat, persistent muscle spasms, seizures), sudden
weight gain, signs of lupus (such as rash on nose and
cheeks, new or worsening joint pain).
taken with sodium bicarbonate, large doses of calcium from your
diet, medications, or supplements can rarely cause a serious
problem called milk-alkali syndrome. Ask your doctor or pharmacist about
using calcium products safely while you are using this medication.
Tell your doctor right away if any of these rare but serious side effects
occur: dizziness, muscle aches/spasms, mental/mood changes (such as
confusion, irritability, memory problems), vomiting, weakness.
medication may rarely cause a severe intestinal condition (Clostridium
difficile-associated diarrhea) due to a type of bacteria. Do not use anti-diarrhea or opioid medications
if you have any of the following symptoms because these products may make them
worse. Tell your doctor right away if you develop: persistent diarrhea,
abdominal or stomach pain/cramping, fever, blood/mucus in your stool.
proton pump inhibitors (such as omeprazole) have caused vitamin B-12
deficiency. The risk is increased if they are taken every day for a long time
(3 years or longer). Tell your doctor right away if you develop symptoms of
vitamin B-12 deficiency (such as unusual weakness, sore tongue, or
numbness/tingling of the hands/feet).
very serious allergic reaction to this drug is rare. However, get
medical help right away if you notice any symptoms of a serious allergic
reaction, including: rash, itching/swelling (especially of the face/tongue/throat),
severe dizziness, trouble breathing, signs of kidney problems
(such as change in the amount of urine).
is not a complete list of possible side effects. If you notice other effects
not listed above, contact your doctor or pharmacist.
taking omeprazole/sodium bicarbonate, tell your doctor or pharmacist if
you are allergic to it; or to similar drugs (such as esomeprazole, lansoprazole, pantoprazole);
or if you have any other allergies. This product may contain inactive
ingredients, which can cause allergic reactions or other problems. Talk to your
pharmacist for more details.
taking this medication, tell your doctor or pharmacist your medical
history, especially of: conditions affected by the sodium in this medication
(such as congestive heart failure, high blood pressure, swelling/edema), kidney problems
(such as Bartters syndrome, kidney failure), liver disease (such
as cirrhosis), low blood calcium or potassium levels,
metabolic imbalance (such as acid-base balance problems), lupus.
medication contains salt (sodium). Before taking this medication, tell your
doctor or pharmacist if you are on a low-salt diet.
symptoms may actually be signs of a more serious condition. Get medical help
right away if you have: heartburn with lightheadedness/sweating/dizziness,
chest/jaw/arm/shoulder pain (especially with shortness of breath,
unusual sweating), unexplained weight loss.
addition, before you self-treat with this medication, get medical help right
away if you have any of these signs of a serious condition: trouble/pain
swallowing food, bloody vomit, vomit that looks like coffee grounds,
bloody/black stools, heartburn for over 3 months, frequent chest
pain, frequent wheezing (especially with heartburn), nausea/vomiting, stomach
having surgery, tell your doctor or dentist about all the products
you use (including prescription drugs, nonprescription drugs, and herbal
pump inhibitors (such as omeprazole) may increase your risk for bone fractures,
especially with longer use, higher doses, and in older adults. Talk with your
doctor or pharmacist about ways to prevent bone loss/fracture, such as by
taking calcium (such as calcium citrate) and vitamin D supplements.
adults may be more sensitive to the side effects of this drug, especially bone
loss and fractures (see above), and Clostridium difficile infection
(see Side Effects section).
may be more sensitive to the side effects of omeprazole, especially
fever, cough, and infections of the nose/throat/airways.
this medication should be used only when clearly needed. Discuss the risks and
benefits with your doctor.
medication passes into breast milk. The effects on a nursing infant are
unknown. Consult your doctor before breast-feeding.