This product is a combination of aspirin, acetaminophen, and caffeine. It is used for the temporary relief of pain from conditions such as muscle aches, toothaches, menstrual cramps, or headaches (including migraine). Aspirin and acetaminophen relieve pain by keeping your body from making certain natural substances. Caffeine helps increase the effects of aspirin and acetaminophen.
Nausea, vomiting, stomach upset, trouble falling asleep, or a shaky/nervous feeling may occur. If any of these effects persist or worsen, notify your doctor or pharmacist promptly.
If your doctor has directed you to use this medication, remember that he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.
Stop taking this medication and tell your doctor right away if any of these unlikely but serious side effects occur: severe dizziness, fainting, persistent or worsening stomach pain, vomit that looks like coffee grounds, black/bloody stools, ringing in the ears, loss of hearing, irregular/fast heartbeat, signs of kidney problems (such as change in the amount of urine), signs of infection (e.g., persistent sore throat or fever), easy bruising/bleeding.
A very serious allergic reaction to this drug is unlikely, but seek immediate medical attention if it occurs. Symptoms of a serious allergic reaction may include: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.
This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.
Before taking this product, tell your doctor or pharmacist if you are allergic to it; or to aspirin or other NSAIDs (e.g., ibuprofen, naproxen, celecoxib); or to other salicylates (such as choline salicylate); or to acetaminophen; or to caffeine; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.
This product should not be used if you have the following medical condition: aspirin-sensitive asthma (a history of worsening breathing with runny/stuffy nose after taking aspirin or other NSAIDs such as ibuprofen, naproxen).
Before using this medication, tell your doctor or pharmacist your medical history, especially of: asthma, certain blood disorders (e.g., anemia), bleeding or blood clotting problems (e.g., hemophilia, low platelet count), ulcers, gout, poorly controlled diabetes, kidney or liver disease, growths in the nose (nasal polyps), anxiety disorders, insomnia, heart disease (e.g., arrhythmia), high blood pressure, stomach problems (e.g., heartburn, upset stomach, or stomach pain) that do not go away or persist.
Consult your doctor or pharmacist for information on safe use of this product.
Before having surgery or certain medical procedures (such as a heart stress test or a procedure to restore a normal heart rhythm if you have an unusually fast heartbeat), tell your doctor or dentist that you use this medication and about all the products you use (including prescription drugs, nonprescription drugs, and herbal products).
This medicine may cause stomach bleeding. Daily use of alcohol and tobacco, especially when combined with this medicine, may increase your risk for stomach bleeding. Avoid alcohol and stop smoking. Consult your doctor or pharmacist for more information.
Older adults may be more sensitive to the side effects of this drug, especially stomach/intestinal bleeding and ulcers, liver problems, and trouble falling asleep.
Children and teenagers less than 18 years old should not use aspirin, aspirin-containing or aspirin-related medications such as this product for flu symptoms or chickenpox without first consulting a doctor. A rare but serious illness known as Reyes syndrome may occur. Tell your doctor right away if you notice changes in behavior with nausea and vomiting.
Aspirin in this product is not recommended for use during pregnancy. Do not use this product during the last 3 months of pregnancy because of possible harm to an unborn baby or problems during delivery. Consult your doctor before using this medication if you are or think you may be pregnant. Tell your doctor right away if you become pregnant while taking this medication.
This product passes into breast milk and may have undesirable effects on a nursing infant. Consult your doctor before breast-feeding.
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