This medication is used to treat malaria in adults and children. The two ingredients in this medication belong to a class of drugs known as antimalarials. Malaria is an infection caused by mosquito bites received while traveling or living in regions of the world where malaria is common. Malaria parasites enter the body and live in body tissues such as red blood cells or the liver. This medication is used to kill the malaria parasites living inside red blood cells. In some cases you may need to take a different medication (such as primaquine) to kill the malaria parasites living in the liver. Both treatments may be needed for a complete cure and to avoid the return of infection (relapse). This product is not used to prevent malaria.
The United States Centers for Disease Control provide updated guidelines and travel recommendations for the prevention and treatment of malaria in different parts of the world. Discuss the most recent information with your doctor before starting treatment with this medication.
Headache dizziness loss of appetite weakness fever chills tiredness muscle/joint pain nausea vomiting abdominal pain cough and trouble sleeping may occur. If any of these effects persist after stopping the medication or if these effects worsen while taking this medication tell your doctor or pharmacist promptly.
Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.
Seek immediate medical attention if any of these rare but very serious side effects occur: chest pain severe dizziness fainting fast/irregular/pounding heartbeat.
A very serious allergic reaction to this drug is rare. However seek immediate medical attention if you notice any symptoms of a serious allergic reaction including: rash itching/swelling (especially of the face/tongue/throat) severe dizziness trouble breathing.
This is not a complete list of possible side effects. If you notice other effects not listed above contact your doctor or pharmacist.
Before taking artemether/lumefantrine tell your doctor or pharmacist if you are allergic to artemether or lumefantrine; or if you have any other allergies. This product may contain inactive ingredients which can cause allergic reactions or other problems. Talk to your pharmacist for more details.
Before using this medication tell your doctor or pharmacist your medical history especially of: recent use (within the past month) of any medication to prevent or treat malaria (such as halofantrine quinine or quinidine) kidney problems liver problems.
Artemether/lumefantrine may cause a condition that affects the heart rhythm (QT prolongation). QT prolongation can rarely cause serious (rarely fatal) fast/irregular heartbeat and other symptoms (such as severe dizziness fainting) that need medical attention right away.
The risk of QT prolongation may be increased if you have certain medical conditions or are taking other drugs that may cause QT prolongation. Before using artemether/lumefantrine tell your doctor or pharmacist of all the drugs you take and if you have any of the following conditions: certain heart problems (heart failure slow heartbeat QT prolongation in the EKG) family history of certain heart problems (QT prolongation in the EKG sudden cardiac death).
Low levels of potassium or magnesium in the blood may also increase your risk of QT prolongation. This risk may increase if you use certain drugs (such as diuretics/"water pills") or if you have conditions such as severe sweating diarrhea or vomiting. Talk to your doctor about using artemether/lumefantrine safely.
This drug may make you feel dizzy or tired or weak. Alcohol or marijuana (cannabis) can make you more dizzy or tired. Do not drive use machinery or do anything that needs alertness until you can do it safely. Limit alcoholic beverages. Talk to your doctor if you are using marijuana (cannabis).
Before having surgery tell your doctor or dentist about all the products you use (including prescription drugs nonprescription drugs and herbal products).
Older adults may be more sensitive to the side effects of this drug especially QT prolongation (see above).
During pregnancy this medication should be used only when clearly needed. Discuss the risks and benefits with your doctor.
It is unknown if this medication passes into breast milk. Consult your doctor before breast-feeding.